The Marvels by Brian Selznick
While on a journey at sea, a boy, Billy Marvel survives a shipwreck. He then finds work in a London Theater where his family flourishes for many generations. Brilliant actress and actors, until one day when young Leontes Marvel is banished from the stage.
Meanwhile a century later, Joseph Jarvis, runs away from school and seek refuge with his estranged Uncle. Uncle Albert's house with it's mysterious contents leads Joseph on a search for clues to his family.
Two families, intertwined together through words and pictures, creates a puzzle that can only be known by reading the story.